Fig. 2: Manhattan plot of association P values for the European ancestry specific meta-analysis of GWAS of circulating total-tau levels. | Communications Biology

Fig. 2: Manhattan plot of association P values for the European ancestry specific meta-analysis of GWAS of circulating total-tau levels.

From: Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels

Fig. 2: Manhattan plot of association P values for the European ancestry specific meta-analysis of GWAS of circulating total-tau levels.The alternative text for this image may have been generated using AI.

The –log10(P)-value for each single nucleotide variant on the y axis is plotted against the build 37 genomic position on the x axis (chromosomal coordinate). The dashed horizontal red line indicates the genome-wide significance threshold of P = 5 × 10−8 and the dashed horizontal black line indicates the threshold of P = 5 × 10−7. The y axis was truncated for ease of interpretation.

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