Fig. 4: Changes in proteins involved in carbohydrate metabolism in AMS.
From: Proteomic and clinical biomarkers for acute mountain sickness in a longitudinal cohort
The log2FC of proteins in glycolysis (light purple background and arrows), gluconeogenesis (light pink background and arrows), the TCA cycle (light green background and arrows), and glycogen synthesis and degradation (light orange background and arrows) in the following four comparison groups are shown in the diamond shape: pathogenesis (path, pink background, AMS4k: n = 30, AMS1k: n = 30), protection (prot, dark blue background, nAMS4k: n = 23, nAMS1k: n = 23), prediction (pred, dark green background, AMS1k: n = 30, nAMS1k: n = 23), and diagnosis (diag, yellow background, AMS4k: n = 30, nAMS4k: n = 23). Carbohydrate metabolism was dysregulated in individuals after ascension to high altitude. The statistical methods were used paired/unpaired t test or Welch’s t test. TCA tricarboxylic acid cycle.
