Fig. 5: Effect of combination of anti-aging interventions (dietary restriction (DR); co-administration of berberine, fucoxanthin, and rapamycin (3G); low ambient temperature (18 °C); living in constant darkness (DD) conditions) on the level of total lipids in w/w and E(z)/w flies. | Communications Biology

Fig. 5: Effect of combination of anti-aging interventions (dietary restriction (DR); co-administration of berberine, fucoxanthin, and rapamycin (3G); low ambient temperature (18 °C); living in constant darkness (DD) conditions) on the level of total lipids in w/w and E(z)/w flies.

From: Molecular mechanisms of exceptional lifespan increase of Drosophila melanogaster with different genotypes after combinations of pro-longevity interventions

Fig. 5: Effect of combination of anti-aging interventions (dietary restriction (DR); co-administration of berberine, fucoxanthin, and rapamycin (3G); low ambient temperature (18 °C); living in constant darkness (DD) conditions) on the level of total lipids in w/w and E(z)/w flies.

a Males. b Females. Control conditions: normal diet, 25 °C, and 12 h light: 12 h dark cycle. Each data point represents a mean of 8–12 biological replicates ± SEM. Plots show individual data points (circles), means (squares), and standard errors (vertical lines). *p < 0.05 compared with age-matched w/w flies, #p < 0.05 compared with the flies of the previous age point, ^p < 0.05 compared with age-matched w/w flies on the same conditions, &p < 0.05 compared with w/w flies on the same conditions. All source data underlying the graphs are presented in the Supplementary Data 1.

Back to article page