Fig. 7: Age-dependent changes in the expression profiles measured for genes participating in KEGG pathways in males and females of both genotypes (w/w and E(z)/w). | Communications Biology

Fig. 7: Age-dependent changes in the expression profiles measured for genes participating in KEGG pathways in males and females of both genotypes (w/w and E(z)/w).

From: Molecular mechanisms of exceptional lifespan increase of Drosophila melanogaster with different genotypes after combinations of pro-longevity interventions

Fig. 7: Age-dependent changes in the expression profiles measured for genes participating in KEGG pathways in males and females of both genotypes (w/w and E(z)/w).

Cell borders demonstrate enrichment FDR-value (Fisher’s exact test) for a pathway (best value among the enrichments for top-50, 100, etc. DEGs). The red border indicates that a KEGG pathway is predominantly enriched with upregulated genes; the blue border—with downregulated genes. The presented data include genes with average read counts per million (CPM) > 1.

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