Fig. 4: Principal coordinate analyses (PCoA) of gene presence/absence data.
From: A 16th century Escherichia coli draft genome associated with an opportunistic bile infection

The accessory genome (a, c) and identified virulence genes (b, d) were clustered using a binary distance. Phylogroups were identified using Clermont Typing59 while pathovars were determined using available metadata from the Patric49 database. The ancient genome is indicated by the black arrow. In both binary distances were calculated prior to create the PCoA.