Table 4 Genetic correlation using a leave-one-out analysis approach for hormone-sensitive cancers using bivariate LDSC in the UKB.
From: Considering hormone-sensitive cancers as a single disease in the UK biobank reveals shared aetiology
Cancer types | Women breast cancer | Prostate cancer | Uterine cancer | Colon & rectum | Cancer of kidney | Multiple myeloma |
|---|---|---|---|---|---|---|
Hormonal cancer (as a single disease) | 0.6796 (0.0568) | 0.7759 (0.0474) | 0.4522 (0.1637) | 0.1551 (0.1254) | −0.0786 (0.2362) | 0.1129 (0.2056) |
Hormonal cancer excluding breast cancer | 0.1662 (0.0930) | −0.0152 (0.1241) | −0.0088 (0.2290) | 0.1926 (0.2295) | ||
Hormonal cancer excluding prostate cancer | 0.2209 (0.1101) | 0.3061 (0.1597) | 0.0645 (0.2853) | 0.0526 (0.2508) | ||
Hormonal cancer excluding ovarian cancer | 0.1208 (0.1247) | −0.1960 (0.2324) | 0.0692 (0.2031) | |||
Hormonal cancer excluding uterine cancer | 0.3487 (0.1889) | 0.1666 (0.1229) | −0.1117 (0.2360) | 0.1520 (0.2096) | ||
Hormonal cancer excluding thyroid cancer | 0.1629 (0.1289) | −0.0561 (0.2386) | 0.0605 (0.2108) |
