Table 1 The list of Aedes aegypti genes with m⁶A sites, which were differentially expressed in response to DENV infection.

From: N⁶-methyladenosine modification of the Aedes aegypti transcriptome and its alteration upon dengue virus infection in Aag2 cell line

Name	Gene description	Fold change	p-value	DENV-infected (RPKM)	Mock (RPKM)	m⁶A Peak
AAEL026586	Unspecified product	179.5	3.57E–03	0.090	0.000	Peaks 1170, 1171, 1172, 1173, 1174, 1175
AAEL025779	SUMO-conjugating enzyme UBC9-B	10.01	5.28E–03	0.100	0.010	Peak 5676
AAEL001548	Glucosyl/glucuronosyl transferases	2.97	3.88E–03	0.180	0.070	Peak 75
AAEL002737	Cytochrome c oxidase, subunit VIIC, putative	2.92	1.84E–07	2.450	1.090	Peak 419
AAEL010801	Cytochrome b-c1 complex subunit 6	2.52	4.63E–10	3.780	1.960	Peak 2602
AAEL020290	60S ribosomal protein L39	2.46	9.30E–09	21.180	11.470	Peak 3632
AAEL013320	Translocon-associated protein, delta subunit	2.21	2.07E–06	2.830	1.760	Peak 2056
AAEL005414	ER membrane protein complex subunit 6	2.19	1.49E–07	3.780	2.260	Peak 5123
AAEL012629	Deoxyuridine 5′-triphosphate nucleotidohydrolase	2.11	3.23E–04	1.270	0.780	Peak 1207
AAEL012010	Conserved hypothetical protein	2.1	2.62E–06	1.770	1.100	Peak 3237
AAEL026055	Unspecified product	−2	0.04	0.070	0.180	Peaks 893, 894, 895
AAEL007801	Exonuclease	−2.03	9.21E–05	0.530	1.440	Peak 2577
AAEL019660	Zwei Ig domain protein zig-8-like isoform X2	−2.07	1.15E–03	0.070	0.170	Peaks 2648, 2649, 2650
AAEL014064	Glutaredoxin, putative	−2.1	2.62E–06	12.950	35.310	Peak 1640
AAEL028092	Fibroblast growth factor receptor homologue 1	−2.27	2.35E–03	0.060	0.180	Peak 5095
AAEL020452	Titin-like protein	−2.44	4.00E–02	0.005	0.020	Peaks 249, 250
AAEL019573	Hemicentin-1	−3.02	8.11E–03	0.020	0.070	Peak 2187
AAEL008811	NADH dehydrogenase 3	−3.36	2.77E–07	2.320	10.690	Peak 5723
AAEL004711	Testis specific leucine rich repeat protein	−3.64	8.32E–03	0.040	0.190	Peak 1555
AAEL005072	MRAS2, putative	−3.84	0.02	0.020	0.080	Peak 5390
AAEL006650	Potassium channel beta	−3.9	6.93E–03	0.009	0.050	Peak 2792
AAEL009825	60S ribosomal protein L13a	−4.83	4.00E–02	0.030	0.210	Peak 5624
AAEL021404	Unspecified product	−5.02	1.00E–02	0.010	0.090	Peak 5605
AAEL014303	Neuroligin	−12.64	3.78E–03	0.002	0.030	Peak 936
AAEL002518	Glutamate receptor, ionotropic kainate 1, 2, 3	−37.12	0.05	0.000	0.010	Peak 4351
AAEL020891	Vacuolar protein sorting-associated protein 13B	−359.05	5.54E–04	0.000	0.080	Peak 5667

Only four genes (in italic) showed differential m⁶A and gene expression upon DENV infection.

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Table 1 The list of Aedes aegypti genes with m⁶A sites, which were differentially expressed in response to DENV infection.

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