Table 4 Prediction results of different methods on three constructed independent test datasets.

From: Protein–protein interaction and non-interaction predictions using gene sequence natural vector

Method

Acc. (%)

Pre. (%)

Sen. (%)

MCC (%)

F-score (%)

S. cerevisiae

 Natural vector difference

78.43

83.80

70.49

57.60

76.57

 Codon frequency difference

91.90

90.38

93.78

83.86

92.05

 our method (SVM-NVDT)

99.20

99.35

99.03

98.39

99.19

D. melanogaster

 Natural vector difference

79.78

84.87

72.47

60.20

78.18

 Codon frequency difference

89.04

89.71

88.20

78.10

88.95

 our method (SVM-NVDT)

94.94

97.62

92.13

90.03

94.80

H. Pylori

 Natural vector difference

71.60

71.18

71.19

43.21

71.49

 Codon frequency difference

72.84

79.37

61.73

46.85

69.44

 our method (SVM-NVDT)

98.56

98.36

98.77

97.12

98.56

  1. Note: Natural vector difference method58. Codon frequency difference57.