Fig. 6: Cardiomyocyte-specific knock out of CITED4 impacts regional tissue helicity changes. | Communications Biology

Fig. 6: Cardiomyocyte-specific knock out of CITED4 impacts regional tissue helicity changes.

From: Exercise-induced CITED4 expression is necessary for regional remodeling of cardiac microstructural tissue helicity

Fig. 6: Cardiomyocyte-specific knock out of CITED4 impacts regional tissue helicity changes.The alternative text for this image may have been generated using AI.

a Helix angle changes differ significantly between groups. b An analysis of helicity between all groups of cohort 2. c Images of DAPI and CITED4 staining of representative mice from cohort 2. d Quantification of CITED4/DAPI using RNA-FISH with cohort 2. Two-way ANOVA used for multivariant analyses *P < 0.05, **P < 0.01, ***P < 0.001. Data are presented min to max. Within each box, horizontal black and red lines denote median values; boxes extend from the 25th to the 75th percentile of each group’s distribution of values.

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