Fig. 4: Task-driven functional mapping of PCC. | Communications Biology

Fig. 4: Task-driven functional mapping of PCC.

From: Dual PET-fMRI reveals a link between neuroinflammation, amyloid binding and compensatory task-related brain activity in Alzheimer’s disease

Fig. 4: Task-driven functional mapping of PCC.The alternative text for this image may have been generated using AI.

a fMRI task design, a total of 6 visual stimulus types were presented. Each run comprised 18 pseudo-randomized blocks with 3 blocks per category of objects. Each block was composed of 20 images, each one presented for ~800 ms followed by a ~200 ms of interstimulus interval which represents an individual duration of 20 s per block. Each block was separated by 10-s fixation. Subjects performed a 1-back task, being instructed to press a button every time the image being presented was the same that had been presented immediately before. b Sample images from different categories used on the fMRI task. Faces stimuli were taken from the FACES database; Bodies stimuli were selected from Bochum Emotional Stimulus Set database and Place stimuli were available on the Computational Visual Cognition Laboratory. c Behavioural metrics, dprime and reaction times (RT), obtained for both AD and controls in the functional task.

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