Fig. 4: GSEA analysis of model predictions based on PageRank score.
From: Predicting genes associated with RNA methylation pathways using machine learning
Personalised PageRank score of all human genes was computed using PPI data from STRING, starting from previously known RNA methylation genes. Black vertical lines in the middle plot indicate the position of model predictions in the resulted ranking. A strong positive enrichment (NES = 1.605, P = 0.0001) was obtained for predicted genes, corroborating a close functional association with RNA methylation pathways.
