Fig. 4: LC-HRMS analysis for the determination of interaction of Probe 10 with the different isoenzymes of ALDH1A. | Communications Biology

Fig. 4: LC-HRMS analysis for the determination of interaction of Probe 10 with the different isoenzymes of ALDH1A.

From: Curcumin-based-fluorescent probes targeting ALDH1A3 as a promising tool for glioblastoma precision surgery and early diagnosis

Fig. 4

LC-HRMS results after 1 h of incubation of single isoenzyme with Probe 10 in presence of ALDH1A1, ALDH1A2 and ALDH1A3. It is possible to appreciate the formation of the corresponding acid (Probe 10-COOH) for 1A1 and 1A2 but not for ALDH1A3. (TIC total ion current).

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