Fig. 5: Analysis of differentially expressed genes in radio adaptive response. | Communications Biology

Fig. 5: Analysis of differentially expressed genes in radio adaptive response.

From: Low dose rate γ-irradiation protects fruit fly chromosomes from double strand breaks and telomere fusions by reducing the esi-RNA biogenesis factor Loquacious

Fig. 5

a Representation of the Venn diagram including all differentially expressed genes from 0.4 Gy LDR + 10 Gy vs. 10 Gy, 0.4 Gy LDR + 10 Gy vs. 0.4 Gy LDR and 10 Gy vs. 0.4 Gy LDR comparisons. Only a very low percentage of genes were in common among all comparisons. A complete list of differentially expressed genes is provided in the Supplementary Data 2, 3 and 5. b Heat map representing the differentially expressed genes from 0.4 Gy LDR + 10 Gy vs. 10 Gy comparison belonging to “RNA processing” biological process obtained from DAVID functional enrichment analysis (Supplementary Data 6). The analysis was performed on three biological replicates obtained from three independent experiments, namely 1, 2, and 3 from the 10 Gy (B) and 0.4 Gy LDR + 10 Gy (D) conditions. A color-coded scale for the normalized expression values is used: red and blue represent high and low expression levels, respectively.

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