Fig. 4: Inhibition of MeA did not block maternal aggression but prevented its increase during the second day of testing.

In Group 1, injected with CNO in PPD4 and VEH in PPD5, the ANOVA showed significant differences between PPD4 and PPD5, with an increase in the total duration of aggression during the second session of testing (a) and a trend towards a decrease in latency to attack on the second day of testing (c). For Group 2, injected with Veh in PPD4 and CNO in PPD5, the ANOVA did not reveal significant differences between studied days in the total amount of time (b) or the latency to attack (d). Data are represented as mean ± SEM; *p ≤ 0.05, #p = 0.051. CNO clozapine N-oxide, Veh vehicle.