Fig. 7: In situ characterization of Angptl7 mRNA in WT and Angptl7 KO mouse eyes.
From: ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma
Angptl7 mRNA was not expressed in any ocular tissue in Angptl7 KO mice whereas it was expressed in TM, cornea, and sclera of WT mice as shown by in situ hybridization (RNAscope). Brightfield images showing following probes. a Negative control: DapB. b Positive control: Ubc (red). c WT mice: Angptl7 (red), and (d) Angptl7 KO mice: Angptl7 (no signal). Scale bars represent 100 μm.
