Fig. 4: Cas using GC-rich PAMs also shows more overlap with functional annotations on the X chromosome. | Communications Biology

Fig. 4: Cas using GC-rich PAMs also shows more overlap with functional annotations on the X chromosome.

From: Contribution of CRISPRable DNA to human complex traits

Fig. 4

The rows represent Cas annotations on the X chromosome, while the columns represent gene annotations (from UCSC), epigenomic markers (from Roadmap), and regulatory elements (from Ensembl). The odds ratio (OR) was calculated by Fisher’s Exact test on n = 125,497 SNPs. The plot shows log(OR), in which blue indicates OR >1.

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