Fig. 3: Normal B cell development in the absence of NDRG1.
From: NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance
a Representative flow cytometry plots of adult WT (blue) and Ndrg1−/− (green) mice, showing Hardy B cell fractions in BM (a), and splenic (b) and peritoneal (c) B cell subsets. d Quantification of absolute BM B cell numbers as gated in (a). e Quantification of B cell subsets, transitional (trans), transitional populations (T1–T3), marginal zone (MZ) and follicular (Fo) numbers in the spleen and total B cells in MLNs as gated in (b). Points are individual mice, lines represent means with 95% CI error bars and are representative of three independent experiments, each with 3–6 mice per group. f Serum Ig levels from WT and Ndrg1−/− mice determined by ELISA. Points are individual mice and lines represent means with 95% CI error bars with 12–16 mice per group. Dotted line represents 1.5× interpolated background absorbance.
