Fig. 5: Compound 6641 treatment increases bone formation in female mice.
From: Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2
a Trabecular micro-CT parameters in lumbar vertebrae of vehicle- and compound-treated female mice. b Gene expression levels of osteoblast markers in tibias from vehicle- and compound-treated female mice measured by quantitative RT-PCR. Twelve and fifteen mice were used in the vehicle and compound groups respectively. qRT-PCR data are normalized to control group and expressed as mean ± SEM. *p < 0.05, ***p < 0.001 vs. vehicle using Student’s t-test.
