Fig. 1: Single-cell RNA sequencing (scRNA-seq) analysis reveals cellular heterogeneity of proximal adjacent (PA) and calcified atherosclerotic core (AC) portions of plaques.

UMAP clustering plots showing a 19 color-coded cell clusters, b different groups, and c 8 cell populations of a total of 35,021 individual cells based on gene expression. d Bar chart of the relative frequency of different cell types in PA and AC groups. e Violin plots of signature genes of different cell type confirmed cluster identities.