Fig. 3: REEs target similar genes enriched with DNA replication-related functions across the early stages of embryogenesis.
From: Recurrent RNA edits in human preimplantation potentially enhance maternal mRNA clearance
a Definition of REE-targeted genes. Note that for further filtering for more reliable results, we used a more stringent criterion (edited by at least one REE in ≥80% of samples) than used for the definition of REEs. b Counts of REE-targeted genes per stage. c Sankey plot describing the number of REE-targeted genes passed to subsequent early stages. For clarity, only REE-targeted genes observed in at least one of the two stages appear in each subplot. d Cross-stage (≥3 stages) enriched functions of REE-targeted genes. Note that we performed enrichment analyses on 3'-UTR- and intronic-REE-targeted genes separately, and discovered cross-stage enriched functions only for the former (Methods). All p values were Benjamini–Hochberg-adjusted (BH-adjusted).
