Table 3 Common upregulated and downregulated proteins in THRSP KO and OE mice involved in Wnt signaling.
Mapped IDs | Gene ID | Protein class | THRSP KO | THRSP OE |
|---|---|---|---|---|
Acta2 | HUMAN | HGNC = 9393|UniProtKB=P17252 | Actin and actin-related protein (PC00039) | –2.8117 | –0.5124 |
Actb | HUMAN | HGNC = 29529|UniProtKB=Q9BZK7 | Actin and actin-related protein (PC00039) | –5.7398 | –1.5119 |
Actc1 | HUMAN | HGNC = 11105|UniProtKB=Q8TAQ2 | Actin and actin-related protein (PC00039) | –5.3626 | –2.4216 |
Actg1 | HUMAN | HGNC = 11106|UniProtKB=Q96GM5 | Actin and actin-related protein (PC00039) | –5.5769 | –1.6339 |
Acvr1b | HUMAN | HGNC = 9399|UniProtKB=Q05655 | Serine/threonine-protein kinase receptor (PC00205) | – | 1.5138 |
Apc | HUMAN | HGNC = 2514|UniProtKB=P35222 |  | – | 0.9016 |
Arhgef6 | HUMAN | HGNC = 4853|UniProtKB=Q92769 | Guanyl-nucleotide exchange factor (PC00113) | – | –0.8640 |
Arrb1 | HUMAN | HGNC = 132|UniProtKB=P60709 | Scaffold/adapter protein (PC00226) | 1.3168 | – |
Cdh2 | HUMAN | HGNC = 292|UniProtKB=P30520 | Cadherin (PC00057) | 1.2180 | – |
Cdh4 | HUMAN | HGNC = 2510|UniProtKB=P26232 | Cadherin (PC00057) | 0.8791 | – |
Csnk1a1 | HUMAN | HGNC = 15906|UniProtKB=A7E2Y1 | Non-receptor serine/threonine-protein kinase (PC00167) | – | –1.8498 |
Ctnna1 | HUMAN | HGNC = 685|UniProtKB=Q15052 | Non-motor actin-binding protein (PC00165) | – | 1.6630 |
Ctnna2 | HUMAN | HGNC = 4405|UniProtKB=P63215 | Non-motor actin-binding protein (PC00165) | –0.9199 | 1.4648 |
Ctnnb1 | HUMAN | HGNC = 9300|UniProtKB=P62714 |  | – | 1.2173 |
Gnb1 | HUMAN | HGNC = 2454|UniProtKB=Q9HCP0 | Heterotrimeric G-protein (PC00117) | 1.3159 | –1.4755 |
Gnb2 | HUMAN | HGNC = 4410|UniProtKB=O60262 | Heterotrimeric G-protein (PC00117) | 1.2958 | –1.3393 |
Gnb4 | HUMAN | HGNC = 11100|UniProtKB=P51532 | Heterotrimeric G-protein (PC00117) | 1.7868 | –1.5291 |
Gng12 | HUMAN | HGNC = 9395|UniProtKB=P05771 | Heterotrimeric G-protein (PC00117) | –2.6507 | –1.1861 |
Gng2 | HUMAN | HGNC = 15906|UniProtKB=A7E2Y1 | Heterotrimeric G-protein (PC00117) | –1.2217 | – |
Gng3 | HUMAN | HGNC = 9395|UniProtKB=P05771 | Heterotrimeric G-protein (PC00117) | –2.8255 | –1.0286 |
Gng7 | HUMAN | HGNC = 11103|UniProtKB=Q12824 | Heterotrimeric G-protein (PC00117) | –3.6163 | –1.0665 |
Hdac2 | HUMAN | HGNC = 11102|UniProtKB=Q9NZC9 | Histone modifying enzyme (PC00261) | – | 1.1406 |
Itpr1 | HUMAN | HGNC = 4410|UniProtKB=O60262 | Ligand-gated ion channel (PC00141) | –1.0551 | – |
Ppp2cb | HUMAN | HGNC = 132|UniProtKB=P60709 | Protein phosphatase (PC00195) | – | –1.0362 |
Ppp3ca | HUMAN | HGNC = 20731|UniProtKB=Q9HAV0 | Protein phosphatase (PC00195) | –2.8295 | –1.9689 |
Ppp3cb | HUMAN | HGNC = 1768|UniProtKB=Q9ULB4 | Protein phosphatase (PC00195) | –3.6034 | –2.6280 |
Ppp3cc | HUMAN | HGNC = 9314|UniProtKB=Q08209 | Protein phosphatase (PC00195) | –2.0380 | – |
Ppp3r1 | HUMAN | HGNC = 20731|UniProtKB=Q9HAV0 |  | –0.9115 | – |
Prkca | HUMAN | HGNC = 9316|UniProtKB=P48454 | Non-receptor serine/threonine-protein kinase (PC00167) | –2.3693 | –1.9847 |
Prkcb | HUMAN | HGNC = 4404|UniProtKB=P59768 | Non-receptor serine/threonine-protein kinase (PC00167) | –1.0276 | –1.1734 |
Prkcd | HUMAN | HGNC = 9314|UniProtKB=Q08209 | Non-receptor serine/threonine-protein kinase (PC00167) | – | 1.2855 |
Prkce | HUMAN | HGNC = 9315|UniProtKB=P16298 | Non-receptor serine/threonine-protein kinase (PC00167) | –2.2312 | – |
Prkcg | HUMAN | HGNC = 9393|UniProtKB=P17252 | Non-receptor serine/threonine-protein kinase (PC00167) | – | –2.1606 |
Smarca4 | HUMAN | HGNC = 4405|UniProtKB=P63215 | DNA helicase (PC00011) | –1.0439 | –1.1084 |
Smarcb1 | HUMAN | HGNC = 4396|UniProtKB=P62873 | DNA metabolism protein (PC00009) | 0.8791 | – |
Smarcc2 | HUMAN | HGNC = 1759|UniProtKB=P19022 | chromatin/chromatin-binding, or -regulatory protein (PC00077) | 1.1382 | 1.6549 |
Smarcd1 | HUMAN | HGNC = 2454|UniProtKB=Q9HCP0 | chromatin/chromatin-binding, or -regulatory protein (PC00077) | 1.0421 | – |
