Fig. 5: CTX-M-14 Y105W enzyme structure. | Communications Biology

Fig. 5: CTX-M-14 Y105W enzyme structure.

From: Mapping the determinants of catalysis and substrate specificity of the antibiotic resistance enzyme CTX-M β-lactamase

Fig. 5: CTX-M-14 Y105W enzyme structure.The alternative text for this image may have been generated using AI.

a CTX-M-14 Y105W enzyme structure (blue, PDB: 7UON) determined at 1.35 Å superimposed on wild-type CTX-M-14 (tan, PDB: 1YLT). Note that the tryptophan assumes an essentially identical position as the wild-type tyrosine. b Polder map of 7UON (3.0σ), constructed with Trp105 omitted, which demonstrates the certainty of the positioning of Trp105.

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