Fig. 5: IHC and survival analysis of MC markers. | Communications Biology

Fig. 5: IHC and survival analysis of MC markers.

From: Single-cell profiling reveals differences between human classical adenocarcinoma and mucinous adenocarcinoma

Fig. 5

a Representative images of IHC staining of CEACAM6, REG4, FCGBP, SPINK4 and MUC2 expression in paired MC or AC cancer tissues and corresponding normal tissues. Scale bar, 100 μm. b Differential analysis of CEACAM6, REG4, FCGBP, SPINK4 and MUC2 levels in paired MC cancer tissues and normal tissues (n = 9 biologically independent patients) and AC cancer tissues and normal tissues (n = 9 biologically independent patients). Statistical analyses were performed by a nonparametric test followed by the Mann‒Whitney test. All the bars represent the mean ± S.D. c Kaplan‒Meier survival curves were generated for the top 20 DEGs by comparing groups of high (red line) and low (blue line) gene expression. The dotted line represents the 95% confidence interval. p < 0.05 according to the log-rank test.

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