Fig. 3: Gene expression heterogeneity of fibroblasts. | Communications Biology

Fig. 3: Gene expression heterogeneity of fibroblasts.

From: A vein wall cell atlas of murine venous thrombosis determined by single-cell RNA sequencing

Fig. 3

a UMAP plot of sub-populations in fibroblasts of sham and DVT data combined. b Relative distribution of sub-populations in sham and DVT groups. c GO analysis of each fibroblast sub-population in comparison to the other two sub-populations. d Heatmap of the top 15 enriched genes in each fibroblast subpopulation in comparison to the other two sub-populations. e Volcano plot of DEGs in total fibroblasts (DVT vs sham group). f Heatmap of the top 25 up- and downregulated genes in DVT compared to sham group. Up- and downregulated genes were separate by a red line. g GSEA of the altered gene sets in DVT versus sham group.

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