Fig. 6: Phagocytosis is induced in response to eLNP stimulation.

a, b Phagocytosis is induced in cDC2, cDC1, CD14^dim CD16⁺ monocytes. Phagocytosis measured using fluorescent beads and multiparametric flow cytometry. PBMCs were incubated overnight with stimulus and with beads for a further 3 h. Dotted grey line represents an example of a young donor unstimulated. Solid grey represents an example of a young donor stimulated with eLNP. Dotted blue line represents an example of an older donor unstimulated. Solid blue represents an example of an older donor stimulated with eLNP. Each individual circle represents one individual subject. n = 9, *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001 by non-parametric Mann Whitney T-test.