Fig. 3: Black module contained co-expressed CNV-lncRNAs and CHD genes. | Communications Biology

Fig. 3: Black module contained co-expressed CNV-lncRNAs and CHD genes.

From: Copy number variation-associated lncRNAs may contribute to the etiologies of congenital heart disease

Fig. 3: Black module contained co-expressed CNV-lncRNAs and CHD genes.The alternative text for this image may have been generated using AI.

a Non-syndromic associated CNVs (n = 19), co-expressed CNV-lncRNAs (n = 30, distributing in 10 CNVs) and 12 CHD genes in heart-correlated black module are shown in the circos plot. The colors of CNVs represent CNV types. The colors of lines represent the Pearson correlation coefficient (calculated with human organ developmental dataset, n = 313) of each gene pair. Two hub CNV-lncRNAs in the black module are in bold font. b Correlations between CNV-lncRNAs and the CHD subtypes in the black module. These relationships are identified based on the intersection of CNV-lncRNAs and non-syndromic CHD associated CNVs (Supplementary Data 4).

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