Fig. 6: CD47 expression correlates with DDR genes in human tumors. | Communications Biology

Fig. 6: CD47 expression correlates with DDR genes in human tumors.

From: The DNA damage response pathway regulates the expression of the immune checkpoint CD47

Fig. 6: CD47 expression correlates with DDR genes in human tumors.The alternative text for this image may have been generated using AI.

a Correlation between CD47 and either mre-11, ATM, ATR or RAD50 expression scores in tumor tissue of uveal melanoma (UVM) patients, is illustrated in scatter plots using StarBase. Spearman’s rank-correlation coefficient r and p value are shown. b Summary of rank-correlation coefficients between indicated DDR gene and CD47 expression scores. Lung Squamous Cell Carcinoma (LUSC) represents tumors where CD47 and DDR genes expression do not correlate. UVM uveal melanoma, KICH kidney chromophobe, READ rectum adenocarcinoma, SKCM skin cutaneous melanoma, THYM thymoma, COAD colon adenocarcinoma.

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