Fig. 5: Untargeted metabolomics of rat fracture tissue from successful and compromised bone healing reveal differences in intermediates from the central carbon metabolism. | Communications Biology

Fig. 5: Untargeted metabolomics of rat fracture tissue from successful and compromised bone healing reveal differences in intermediates from the central carbon metabolism.

From: A comprehensive molecular profiling approach reveals metabolic alterations that steer bone tissue regeneration

Fig. 5: Untargeted metabolomics of rat fracture tissue from successful and compromised bone healing reveal differences in intermediates from the central carbon metabolism.

a Heatmap of selected central metabolites from the central carbon metabolism (glycolysis, TCA cycle). Shown are sum over mean normalized LFQ intensities, with following color coding, red= upregulated, white= unchanged between conditions, blue= downregulated, grey= no values. n = 3-5 biological replicates (BR) per group and time-point. b Schematic central metabolic pathway, metabolites that are shown in heatmap are marked by grey and enlarged circles.

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