Fig. 1: LncAABR07053481 is downregulated under hypoxia and associated with apoptosis of BMSCs. | Communications Biology

Fig. 1: LncAABR07053481 is downregulated under hypoxia and associated with apoptosis of BMSCs.

From: LncAABR07053481 inhibits bone marrow mesenchymal stem cell apoptosis and promotes repair following steroid-induced avascular necrosis

Fig. 1

a Cluster analysis of LncRNAs (n = 3). b Location of LncRNA in the genome. c Prediction of LncAABR07053481 coding capability by the coding-potential assessment tool (CPAT). d The expression of the Myc-fused protein was analyzed by immunoblotting with an anti-Myc antibody (n = 3). e, f The relationship between the degree of hypoxia and apoptosis (n = 4). g Expression of LncAABR07053481 under different oxygen concentrations (n = 4). h Detection of LncAABR07053481 expression in the normal femoral head and the area of osteonecrosis by qPCR (n = 6). i Detection of LncAABR07053481 expression in BMSCs at different times after transplantation by qPCR (n = 6). Data were shown as mean ± SD. *P < 0.05; In (h), statistical significance was calculated by Student’s t-test; in (f, g, i), statistical significance was calculated by one-way ANOVA with Tukey’s post hoc tests.

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