Fig. 6: LncAABR07053481-overexpressed BMSCs promote the repair of early SANFH. | Communications Biology

Fig. 6: LncAABR07053481-overexpressed BMSCs promote the repair of early SANFH.

From: LncAABR07053481 inhibits bone marrow mesenchymal stem cell apoptosis and promotes repair following steroid-induced avascular necrosis

Fig. 6

a At 12 weeks after BMSC transplantation, micro-CT was used to analyze the repair of the necrotic area of the femoral head (n = 6). b–d Quantitative analysis of the number of trabeculae, the trabecular thickness, and the volume fraction of new bone tissue (n = 6). e At 12 weeks after BMSC transplantation, H&E and Masson staining were used to evaluate the repair of the necrotic area of the femoral head (n = 6). f At 12 weeks after BMSC transplantation, immunohistochemistry was used to detect osteogenic markers of runt-related transcription factor 2 (Runx2, Cy3 label, red) and osteopontin (OPN, FITC label, green) (n = 6). g Quantitative analysis of Runx2 expression (n = 6). h Quantitative analysis of OPN expression (n = 6). Data were shown as mean ± SD. *P < 0.05; In (b–d, g, h), statistical significance was calculated by one-way ANOVA with Tukey’s post hoc test.

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