Fig. 2: Functional connectivity-based perspective on WM. | Communications Biology

Fig. 2: Functional connectivity-based perspective on WM.

From: Spectrotemporal content of human auditory working memory represented in functional connectivity patterns

Fig. 2

a A hypothesis of how spectrotemporal modulation features such as the “ripple velocity” or ω are represented in auditory WM. Different subregions of auditory cortex located in STC, as well subregions of higher frontoparietal areas connected to each subregion of auditory cortex44,45,46,61,77, could show best sensitivity to different ω values. The connectivity patterns between STC and frontoparietal areas responsive to ripple sounds could, thus, be arranged according to the prefrred or “best” ω (gray dotted arrows). We specifically hypothesized that functional connectivity between STC and frontoparietal areas could be modulated in content specific fashion during WM maintenance (red arrow)16,33. b Regions of interest (ROI) for our connectivity-based MVPAs testing our main hypothesis. The eight major ROIs are shown on a semi-inflated standard brain surface (left hemisphere, lateral and medial views). Each major ROI was further divided to subROIs (average area 157 mm2). The ROI-to-ROI connectivity patterns were defined as the connectivity matrices from across all their subROIs, analogously to our previous MEG studies33,48,49,91. Occipital cortex (OC) was included as a control area. The details of ROI definitions and analysis procedures are provided in Methods. Abbreviations not specified above: IFG inferior frontal gyrus, MFG middle frontal gyrus, PC precentral cortex, SPL superior temporal lobule, SMG supramarginal gyrus, AG angular gyrus.

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