Fig. 6: Gene composition and functional enrichment analysis of each module.

a The percentage of proximal and distal target genes defined by AdaEnsemble (see Method section) in each module. b Circos plot indicates the overlaps between module genes. The inner circle represents the gene lists of each module. Genes that hit multiple lists are coloured in dark orange, and genes unique to a list are shown in light orange. The purple curves inside link identical genes. c Venn diagram demonstrating the gene numbers and overlaps in transcriptionally active modules (left) and transcriptionally repressed modules (right). d GO analyses of genes in transcriptionally active modules (left) and transcriptionally repressed modules (right) (Supplementary Data 10). The top10 enrichment terms in each module are shown. The cell colour corresponds to –log₂ (p-value).