Fig. 2: Broad binding affinity of 1H1.
From: Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants
a, b binding of 1H1 to different spikes (a) or RBDs (b) of SARS-CoV-2 variants as measured by ELISA. Data are shown as the mean values of three replicates. Error bars indicate standard deviation (SD) of at least three biological replicates. c binding kinetics of 1H1 to different spike ECD proteins of SARS-CoV-2 variants as measured by BLI. d binding kinetics of 1H1 to different spike RBD proteins of SARS-CoV-2 variants as measured by BLI. Black lines were the original curves, while colored lines were the fitted curves. KD apparent values are shown for 1H1 IgG binding to spike ECD and RBD proteins using a 1:1 global fit model.
