Table 1 Srr1 and Skb1 are specifically required for isochromosome formation.

From: Fission yeast Srr1 and Skb1 promote isochromosome formation at the centromere

 

Strain #

Translocations

Isochromosomes

Truncations

Total

wild type

TNF5369

1 (3%)

31 (97%)

0 (0%)

32

rad51∆

TNF5411

0 (0%)

72 (92%)

6 (8%)

78

srr1∆ rad51∆

TNF5904

0 (0%)

7 (44%)

9 (56%)

16

skb1∆ rad51∆

TNF5788

0 (0%)

10 (63%)

6 (37%)

16

skb1-FY rad51∆

TNF8391

0 (0%)

22 (69%)

10 (31%)

32

  1. The percentage of each GCR type is shown in the parenthesis. GCR products of wild type have been shown previously36. Some GCR products of rad51∆ have been shown previously32, 36.