Fig. 9: Differential miRNA and mRNA expression between male and female microglia across developmental age. | Communications Biology

Fig. 9: Differential miRNA and mRNA expression between male and female microglia across developmental age.

From: Mouse microglia express unique miRNA-mRNA networks to facilitate age-specific functions in the developing central nervous system

Fig. 9: Differential miRNA and mRNA expression between male and female microglia across developmental age.The alternative text for this image may have been generated using AI.

a Venn diagram comparing differential expression of miRNAs between male and female microglia in each age group. No miRNAs were differentially expressed at any age (FDR < 0.05). b Venn diagram comparing differential expression of mRNA between male and female microglia in each age group. Six mRNAs were identified as differentially expressed in every age group. c qPCR expression of selected miRNA candidates between male and female microglia (n = 3 in each group). Data were analysed by unpaired t tests comparing microglia and CD45−ve bulk group expression for each tested miRNA. No statistically significant differences in expression were observed for any of the tested miRNAs. qPCR data is presented as mean ± SD.

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