Fig. 9: Schematic illustration indicating that JAZF1 safeguards hESCs survival and decidualization by repressing the transcription of G0S2 via restricting G0S2 activator Purβ. | Communications Biology

Fig. 9: Schematic illustration indicating that JAZF1 safeguards hESCs survival and decidualization by repressing the transcription of G0S2 via restricting G0S2 activator Purβ.

From: JAZF1 safeguards human endometrial stromal cells survival and decidualization by repressing the transcription of G0S2

Fig. 9: Schematic illustration indicating that JAZF1 safeguards hESCs survival and decidualization by repressing the transcription of G0S2 via restricting G0S2 activator Purβ.

JAZF1 depletion promotes the transcriptional activation of G0S2 via enhancing Purβ binding to G0S2 promoter, inducing cell death via apoptosis and decidualization defects in human ESCs of RSA patients. ESCs endometrial stromal cells.

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