Fig. 4: Results of group-ICA analysis.

All spatial maps are shown in radiological orientation. a Z-scored group-level spatial maps. b Spatial maps of the first 3 components (upper row) and corresponding t-maps of age-related changes (lower row), corresponding to the output of the mass-univariate modelling step in Fig. 1a. A negative effect of age can be observed in the most representative component voxels. c Distribution of spatial correlations between component spatial maps and corresponding t-maps of age-related changes. The outlier is the component with likely vascular origin (component #5).