Fig. 2: Molecular markers of P. falciparum sulfadoxine-pyrimethamine (SP) resistance in Mozambique. | Communications Biology

Fig. 2: Molecular markers of P. falciparum sulfadoxine-pyrimethamine (SP) resistance in Mozambique.

From: Targeted and whole-genome sequencing reveal a north-south divide in P. falciparum drug resistance markers and genetic structure in Mozambique

Fig. 2: Molecular markers of P. falciparum sulfadoxine-pyrimethamine (SP) resistance in Mozambique.

Frequency of P. falciparum isolates carrying triple mutations in pfdhfr (a), double mutations in pfdhps (b), and quintuple mutations in pfdhfr/phdhps (c) in 2015 and 2018 in seven provinces from Mozambique. For the pfdhps haplotype 436/437/540 (d), frequencies of the different allelic combinations are shown (n = 1365). Frequencies were calculated after excluding mixed genotypes. Data from Sofala was only available for 2015, and from Inhambane and Zambézia for 2018. The error bars represent a 95% confidence interval for the population proportion.

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