Fig. 6: Schematic illustration of ERα-SERPINA3-ANKRD11-HDAC3 pathway.

Schematic showing the proposed mechanism of anti-estrogen-therapy-induced SERPINA3 expression loss driving endocrine resistance in human ER+ breast cancer.

Schematic showing the proposed mechanism of anti-estrogen-therapy-induced SERPINA3 expression loss driving endocrine resistance in human ER+ breast cancer.