Fig. 2: AKAP150 increased in the vlPAG in the CPA model. | Communications Biology

Fig. 2: AKAP150 increased in the vlPAG in the CPA model.

From: Selective activation of AKAP150/TRPV1 in ventrolateral periaqueductal gray GABAergic neurons facilitates conditioned place aversion in male mice

Fig. 2

Immunofluorescence images (a) and western blotting assay (b) showed that the expression of AKAP150 increased obviously in the pinch pain CPA model. Scale bar, 50 μm (n = 3). (***P < 0.001 vs. the control group, two-sample t test, n = 6). Immunofluorescence images (c) and western blotting assay (d) showed that the expression of AKAP150 increased obviously in the morphine-withdrawal CPA model. Scale bar, 50 μm (n = 3). (***P < 0.001 vs. the control group, two-sample t test, n = 6). e Schematic of the vlPAG in different layers of the mesencephalon. Data are shown as the mean ± SEM.

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