Fig. 7: Schematic diagram of the molecular mechanism of NFIB promoting CRC cell proliferation through up-regulation of NAD+ level. | Communications Biology

Fig. 7: Schematic diagram of the molecular mechanism of NFIB promoting CRC cell proliferation through up-regulation of NAD+ level.

From: Downregulation of miR-182-5p by NFIB promotes NAD+ salvage synthesis in colorectal cancer by targeting NAMPT

Fig. 7

Schematic diagram of the molecular mechanism by which NFIB promotes the proliferation of CRC cells. NFIB post-transcriptionally regulates miRNA-182-5p, which then targets NAMPT to inhibit CRC cell proliferation through NAMPT-mediated of NAD+ level.

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