Table. 1 Correlation between NFIB expression and clinicopathological features in cancer tissues from 261 CRC patients.
Features | No. of patients (%) | NFIB level | P value | |
|---|---|---|---|---|
Low (n = 131) No. (%) | High (n = 130) No. (%) | |||
Gender | ||||
  Male | 153(58.6%) | 83(54.2%) | 70(45.8%) | 0.119 |
  Female | 108(41.4%) | 48(44.4%) | 60(55.6%) |  |
Age | ||||
  ≤60 | 131(50.2%) | 73(55.7%) | 58(44.3%) | 0.073 |
  >60 | 130(49.8%) | 58(44.6%) | 72(55.4%) |  |
NAMPT level | ||||
  Low | 168(64.4%) | 92(54.8%) | 76(45.2%) | 0.047 |
  High | 93(35.6%) | 39(41.9%) | 54(58.1%) |  |
Vascular invasion | ||||
  Yes | 99(37.9%) | 51(51.5%) | 48(48.5%) | 0.738 |
  No | 162(62.1%) | 80(49.4%) | 82(50.6%) |  |
Nerve invasion | ||||
  Yes | 57(21.8%) | 30(52.6%) | 27(47.4%) | 0.677 |
  No | 204(78.2%) | 101(49.5%) | 103(50.5%) |  |
Differentiation degree | ||||
  Well | 69(26.4%) | 38(55.1%) | 31(44.9%) | 0.06 |
  Moderate | 98(37.5%) | 55(56.1%) | 43(43.9%) |  |
  Poor | 94(36.0%) | 38(40.4%) | 56(59.6%) |  |
Size (cm) | ||||
  ≤4.8 | 142(54.4%) | 74(52.1%) | 68(47.9%) | 0.498 |
  >4.8 | 119(45.6%) | 57(47.9%) | 62(52.1%) |  |
T stage | ||||
  I | 8(3.1%) | 5(62.5%) | 3(37.5%) | 0.056 |
  II | 49(18.8%) | 32(65.3%) | 17(34.7%) |  |
  III | 189(72.4%) | 89(47.1%) | 100(52.9%) |  |
  IV | 15(5.7%) | 5(33.3%) | 10(66.7%) |  |
T stage | ||||
  I + II | 57(21.8%) | 37(64.9%) | 20(35.1%) | 0.012 |
  III + IV | 204(78.2%) | 94(46.1%) | 110(53.9%) |  |
N stage | ||||
  0 | 156(59.8%) | 87(55.8%) | 69(44.2%) | 0.06 |
  1 | 65(24.9%) | 25(38.5%) | 40(61.5%) |  |
  2 | 40(15.3%) | 19(47.5%) | 21(52.5%) |  |
N stage | ||||
  Negative | 156(59.8%) | 87(55.8%) | 69(44.2%) | 0.028 |
  Positive | 105(40.2%) | 44(41.9%) | 61(58.1%) |  |
Distant metastasis | ||||
  Negative | 256(98.1%) | 129(50.4%) | 127(49.6%) | 0.684 |
  Positive | 5(1.9%) | 2(40.0%) | 3(60.0%) |  |
TNM stage | ||||
  I | 50(19.2%) | 33(66.0%) | 17(34.0%) | 0.042 |
  II | 104(39.8%) | 53(51.0%) | 51(49.0%) |  |
  III | 102(39.1%) | 43(42.2%) | 59(57.8%) |  |
  IV | 5(1.9%) | 2(40.0%) | 3(60.0%) |  |
TNM stage | ||||
  I + II | 154(59.0%) | 86(55.8%) | 68(44.2%) | 0.028 |
  III + IV | 107(41.0%) | 45(42.1%) | 62(57.9%) |  |
