Table 1 Comparison between aminoglycoside resistance genes predicted in pathogenic species and the total collection of predicted genes.
| Â | Â | Pathogens | All species | ||
|---|---|---|---|---|---|
Model | Representative phenotype(s) | Predicted AMEs [unique proteins] | AME Familiesa | Predicted AMEs [unique proteins] | AME Familiesa |
A | AAC(2’)-I | 296 [41] | 6/4 | 4,715 [1,645] | 341/7 |
B | AAC(3)-I | 1,755 [36] | 1/4 | 3,061 [832] | 360/8 |
C | AAC(3)-II, III, VI, VII, VIII, IX | 102,582 [1,028] | 18/6 | 116,274 [6,961] | 1,469/13 |
D | AAC(6’)-I,II | 19,015 [526] | 8/8 | 24,754 [2,248] | 513/9 |
E | AAC(6’)-I | 436,848 [998] | 35/8 | 446,428 [5,021] | 1,185/9 |
F | AAC(6’)-I | 20,899 [110] | 4/6 | 23,087 [886] | 349/8 |
G | APH(2’’)-I | 3,403 [305] | 9/6 | 5,172 [1,251] | 386/6 |
H | APH(3’)-I, II, III, IV, V, VI, VII, VIII, IX, XV + APH(3’’)-I | 231,817 [1,745] | 30/14 | 248,178 [6,005] | 1,146/22 |
I | APH(6)-I + APH(3’)-II | 180,758 [1,286] | 33/4 | 200,146 [9,204] | 1,776/6 |
Total | Â | 997,373 [6,075] | 144/60 | 1,071,815 [34,053] | 7,525/88 |
