Fig. 7: Bi-clustering defines additional gene signatures and sub-populations in canine osteosarcoma.

DOG2 gene expression profiles for (a) ISA signature 1, (b) ISA signature 2, (c) ISA signature 3, and (d) ISA signature 4. Corresponding Kaplan–Meier curves of ISA sample bi-cluster versus all other samples for ISA signature 1 (e), ISA sample bi-cluster 2 (f), ISA signature 3 (g), ISA signature 4 (h). Y-axis is Overall Survival, with medians reported in days from diagnosis.