Fig. 4: Peptide profile differences after 2-weeks of d-Ala-13C3,15N or l-Ala-2,3,3,3-D4 treatment in drinking water compared to control (water only) (n = 4).
From: Biodistribution and racemization of gut-absorbed l/d-alanine in germ-free mice
a, b Pancreatic islets. c, d Pituitary gland. Volcano plots showed results of uncorrected multiple t-tests between treated and control groups. Each data point represents the fold change and p values of log2-transformed, normalized peak intensities in the samples from treated animals compared to control. Data points with larger than 2-fold absolute fold change and/or p values smaller than 0.05 are marked with assigned peptide names and color coded (blue for decrease and red for increase in the treated group compared to control). CLIP: corticotropin-like intermediate peptide. J-peptide: joining peptide.
