Fig. 4: No major differences in the expression of CASPR2 between male and female WT mice. | Communications Biology

Fig. 4: No major differences in the expression of CASPR2 between male and female WT mice.

From: Sexual dimorphism in the social behaviour of Cntnap2-null mice correlates with disrupted synaptic connectivity and increased microglial activity in the anterior cingulate cortex

Fig. 4

a Western blot analysis of lysates from the dorsal prefrontal cortex (dPFC) of P28 WT mice show no major differences in the expression of CASPR2 between male and female (upper part). The expression of MAPK (lower part) was used as a loading control to normalise CASPR2 expression levels. No CASPR2 specific bands were detected in the dPFC from P28 Cntnap2 KO mice. b Quantification shows no statistically significant difference in expression levels of CASPR2 protein between male and female WT dPFC brains. Statistical analysis was done using an unpaired two-tail t test (t = 0.34, df = 6). Male and females: n = 4 for (labelled 1–4 in (a)). Data are represented as means, error bars represent SEM. Uncropped and unedited blot images are shown as Supplementary Fig. 4.

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