Table 1 Model simulation parameters.

Monomers per fiber, \({N}_{\rm {{m}}}\)

200–1100⁵⁴

Monomer persistence length, \({L}_{\rm {{p}}}\)

0.005–1.074 nm⁵⁴

Fibrin radius, \({r}_{{\rm {{fib}}}}\)

0.05 μm³⁰

Temperature, \(T\)

300 K

Normalized contour length multiplier, \(C\)

2.35⁵⁴

Fibrin volume fraction

0.3%⁶⁵

Fibrin network radius

23.8 µm

Platelet radius, \({r}_{\rm {{p}}}\)

1.1 μm¹⁰⁵

Adhesive zone fraction, \({f}_{\rm {{r}}}\)

0.9

Platelet range, \({r}_{{\rm {{fil}}}}\)

2.2 μm¹⁶

Adhesion zone force, \({F}_{0}\)

4 nN^58,59,60

Average platelet density

8 × 10⁵ platelets/mm^3 64

Fibrin fraction initialized near platelets, \({P}_{{\rm {{fnp}}}}\)

0.5 (see Supplementary Note 2.1)

Contraction time

30 min

Number of filopodia per platelet

Discretized truncated lognormal distribution (see the section “Model validation” and Fig. 4)¹⁰⁶.

\({f}_{0}\), force of platelet for zero stiffness

2.2 nN

\(a\), fitting parameter

61

\(b\), fitting parameter

3.6

\(c\), fitting parameter

132

\(d\), fitting parameter

1.4 nN

\(\tau\), force relaxation time

637 s