Fig. 2: Proteomic analysis of ocular posterior pole tissues from LIM and FDM models. | Communications Biology

Fig. 2: Proteomic analysis of ocular posterior pole tissues from LIM and FDM models.

From: Targeting the cochlin/SFRP1/CaMKII axis in the ocular posterior pole prevents the progression of nonpathologic myopia

Fig. 2

Venn diagram of DEGs among experimental groups (a). Heatmap shows the differential protein expression profiling in FDM vs normal, LIM vs Normal, and LIM vs FDM groups (b). Under the premise of P < 0.05, the color scale is set according to the log2 FC of the protein expression levels between the corresponding groups. Volcano maps of DEGs between LIM and normal control groups (c), FDM and normal control groups (d), and LIM and FDM groups (e), with red dots indicating upregulation, green triangle downregulation, gray circle no difference, and blue rhombus the position of cochlin. GO analyses of DEGs among experimental groups (f–h). KEGG analyses of DEGs among experimental groups (i–k). FC fold change of the protein expression levels, DEGs differentially expressed genes, GO Gene Ontology, KEGG Kyoto Encyclopedia of Genes and Genomes.

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