Fig. 5: HLA class I alleles detected in PDX models from pediatric solid cancers. | Communications Biology

Fig. 5: HLA class I alleles detected in PDX models from pediatric solid cancers.

From: A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors

Fig. 5: HLA class I alleles detected in PDX models from pediatric solid cancers.

For each tumor type and molecular subtype, the numbers of alleles in PDX models harboring the corresponding HLA-A, -B and -C alleles are indicated within the boxes (1–11). HLA alleles were grouped according to their supertype-specific binding motifs, unless unclassified (denoted with “NA”), which are indicated at each HLA gene panel, and sorted by descending order of allele frequencies reported from EUR control individuals. Alleles detected only in PDXs derived from non-European (non-EUR) individuals are shown in gray boxes.

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