Fig. 8: Schematic diagrams of conformational equilibria between the outward-facing and post-occluded configurations of hABCB6core and the W546A mutant. | Communications Biology

Fig. 8: Schematic diagrams of conformational equilibria between the outward-facing and post-occluded configurations of hABCB6core and the W546A mutant.

From: W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state

Fig. 8: Schematic diagrams of conformational equilibria between the outward-facing and post-occluded configurations of hABCB6core and the W546A mutant.The alternative text for this image may have been generated using AI.

a–c Subunits are colored blue and cyan. Mg2+/ATP is depicted as an orange oval. Phospholipids are presented as brown heads and yellow tails. Dark-colored states indicate ‘preferred’ forms, while pale-colored states represent ‘unfavorable’ forms.

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